Wednesday, September 26, 2012, 10:15 PM ET

Arizona Diamondbacks at San Francisco Giants
AT&T Park, San Francisco, California

Pitchers:
Diamondbacks LH Wade Miley (16-10, 3.25 ERA) vs. Giants RH Matt Cain (15-5, 2.86)



The Diamondbacks go for their eighth win in 10 games Wednesday, when they take on the National League West champion San Francisco Giants at AT&T Park. San Francisco is 10-3 in their last 13  games overal and 6-2 on a 10-game homestand.

Lefthander Wade Miley is coming off a victory at Colorado on Friday in which he allowed five runs and 10 hits over six innings. In his last three starts, the NL Rookie of the Year candidate surrendered five runs in each of his two wins and only three over seven frames in a loss to San Francisco on Sept. 15. The 25-year-old Miley has won three straight road outings.

Right-haner Matt Cain posted his fifth consecutive win on Sept. 19, when he limited Colorado to one run and four hits in eight innings. The 27-year-old, who has not lost since Aug. 6 at St. Louis, has allowed a total of four runs in 20 1/3 frames over his last three outings. Cain improved to 12-6 lifetime against the Diamondbacks when he yielded one run in five innings on Sept. 14 at Arizona.


Prediction: San Francisco Giants -150